A favorite instrument in the orchestra, a familiar voice in a crowd of people, or the still of a forest floor and then, suddenly, a snapping twig. What mechanisms of our central nervous system draw our attention to these sounds and separate them for analysis or allow them to take control of our behavior? What is the role of early auditory experience in shaping these responses? and perhaps more importantly, what plastic changes in growing brain connections may occur when hearing is disturbed in childhood as it may be with chronic middle ear infections? The approach of our laboratory has been to use modern neuroanatomical techniques to visualize, reconstruct and analyze the development and organization of complex auditory circuits.
Coming soon . .
Henkel CK. Tutorial: autonomic nervous system. MedEdPORTAL. 2010; ():ID8076.
Henkel CK. Creating interactive learning objects with PowerPoint: primer for lecture on the autonomic nervous system. Med Teach. 2010; 32(8):e355-e359.
Willard SL, Friedman DP, Henkel CK, Shively CA. Anterior hippocampal volume is reduced in behaviorally depressed female cynomolgus macaques. Psychoneuroendocrinology. 2009; 34(10):1469-1475.
Alvarado JC, Fuentes-Santamaria V, Henkel CK. Rapid modifications in calretinin immunostaining in the deep layers of the superior colliculus after unilateral cochlear ablation. Hear Res. 2009; 247(1):78-86.
Willard SL, Glover EJ, Friedman DP, Henkel CK, Shively CA. Anterior hippocampal volume is reduced in behaviorally depressed female macaca fascicularis living in social groups [abstract]. Am J Primatol. 2008; 70(Suppl 1):25.
Franklin SR, Brunso-Bechtold JK, Henkel CK. Bilateral cochlear ablation in postnatal rat disrupts development of banded pattern of projections from the dorsal nucleus of the lateral lemniscus to the inferior colliculus. Neuroscience. 2008; 154(1):346-354.
Alvarado JC, Fuentes-Santamaria V, Franklin SR, Brunso-Bechtold JK, Henkel CK. Synaptophysin and insulin-like growth factor-1 immunostaining in the central nucleus of the inferior colliculus in adult ferrets following unilateral cochlear removal: a densitometric analysis. Synapse. 2007; 61(5):288-302.
Johnson JE, Henkel C. Anatomy and contextual learning [abstract]. FASEB J. 2007; 21(5):A140.
Henkel CK, Agee DA, Franklin SR. Blocking spontaneous activity in postnatal rat inferior colliculus perturbs development of afferent compartments [abstract]. Assoc Res Otolaryngol Abstr. 2007; 30():285.
Fuentes-Santamaria V, Alvarado JC, Henkel CK, Brunso-Bechtold JK. Cochlear ablation in adult ferrets results in changes in insulin-like growth factor-1 and synaptophysin immunostaining in the cochlear nucleus. Neuroscience. 2007; 148(4):1033-1047.
Gabriele ML, Shahmoradian SH, French CC, Henkel CK, McHaffie JG. Early segregation of layered projections from the lateral superior olivary nucleus to the central nucleus of the inferior colliculus in the neonatal cat. Brain Res. 2007; 1173():66-77.
Henkel CK, Keiger CJ, Franklin SR, Brunso-Bechtold JK. Development of banded afferent compartments in the inferior colliculus before onset of hearing in ferrets. Neuroscience. 2007; 146(1):225-235.
Willard SL, Glover EJ, Friedman DP, Henkel CK, Shively CA. Reduced anterior hippocampal volume in behaviorally depressed female cynomolgus macaques (Macaca fascicularis) [abstract]. Soc Neurosci Abstr. 2007; 2007(Abstr Viewer):.
Franklin SR, Brunso-Bechtold JK, Henkel CK. Unilateral cochlear ablation before hearing onset disrupts the maintenance of dorsal nucleus of the lateral lemniscus projection patterns in the rat inferior colliculus. Neuroscience. 2006; 143(1):105-115.
Brunso-Bechtold JK, Evans SD, Henkel CK. Synaptogenesis in the inferior colliculus of the pre-hearing postnatal ferret. Hear Res. 2006; 218(1-2):1-4.
Henkel CK. The auditory system. In: Haines DE, ed. Fundamental neuroscience for basic and clinical applications. 3rd ed. Philadelphia: Churchill Livingstone/Elsevier; 2006: 335-349.
Gabriele ML, Fathke RL, Shahmoradian SH, French CC, Henkel CK, McHaffie JG. Segregation of multiple layered projections to the central nucleus of the inferior colliculus in the neonatal cat [abstract]. Soc Neurosci Abstr. 2006; 2006(Abstr Viewer).