Dr. Charles Tegeler’s research deals with the use of ultrasound in the prevention and treatment of stroke, cerebrovascular disorders, and concussion, as well as the use of such methods for assessment of cerebrovascular physiology, performance, and function in a variety of other clinical settings. Many of these projects utilize Dynamic Vascular Analysis (DVA), a new method for analyzing transcranial Doppler ultrasound data. Specific activities with DVA include the use of this method in the settings of sports-related concussion, vasospasm following subarachnoid hemorrhage, obstructive sleep apnea, carotid artery stenting, sickle cell disease, shunt-responsive hydrocephalus, hyperbaric oxygen therapy, treatment with a variety of compounds, and implementation of a DVA Core Reading Center. His group also studies peripheral arterial disease in stroke patients, and the use of an electronic stethoscope and neural network to better identify patients with carotid stenosis. He participates in a variety of clinical stroke prevention and treatment trials, and Phase II of the ongoing North Carolina Stroke Registry. Dr. Tegeler holds the McKinney-Avant Chair in Neurosonology, serves as Medical Director for the Neuroultrasound Laboratory, and is Head of the Section on Stroke, Cerebrovascular Disease, and Neurosonology. He also is Director of the Neurovascular Ultrasound Courses in the Center for Medical Ultrasound, the Fellowship in Stoke, Cerebrovascular Disease, and Neurosonology, and the Neurosonology Mini-Fellowship Program. He has served as Fellowship Director/Mentor for 15 Fellows in Stroke, Cerebrovascular Disease, and Neurosonology. Dr. Tegeler will provide oversight to the Neurology Clinical Rotation.
Coming soon . .
Asimos AW, Johnson AM, Rosamond WD, Price MF, Rose KM, Catellier D, Murphy CV, Singh S, Tegeler CH, Felix A. A multicenter evaluation of the ABCD2 score’s accuracy for predicting early ischemic stroke in admitted patients with transient ischemic attack. Ann Emerg Med. 2010; 55(2):201-210.
Tang R, Tegeler C, Larrimore D, Cowgill S, Kemper KJ. Improving the well-being of nursing leaders through healing touch training. J Altern Complement Med. 2010; 16(8):837-841.
Anderson R, Tegeler C, Camacho F, Parks ME, Toole J. A trial to enhance the effectiveness of community stroke risk screening in North Carolina [abstract]. Stroke. 2009; 40(4):e265.
Rudisill M, Parks ME, Tegeler C, Bushnell C. Education for stroke survivors: extending quality improvement ‘Beyond the Hospital’ [abstract]. Stroke. 2009; 40(4):e138.
Asimos AW, Rosamond WD, Johnson AM, Price MF, Rose KM, Murphy CV, Tegeler CH, Felix A. Early diffusion weighted MRI as a negative predictor for disabling stroke after ABCD2 score risk categorization in transient ischemic attack patients. Stroke. 2009; 40(10):3252-3257.
Tegeler CH, Babikian VL. Ultrasound imaging of the cerebral vasculature. In: Bradley WG, Daroff R, Fenichel G, Jankovic J, eds. Neurology in clinical practice, vol 1. 5th ed. Philadelphia: Butterworth-Heinemann/Elsevier; 2008: 659-679.
Asimos AW, Rosamond WD, Price MF, Johnson A, Felix AC, Tegeler CH, Rose KM, Murphy CV. Ability of the ABCD2 score to predict early stroke and DWI positive MRI in admitted transient ischemic attack patients without a history of prior stroke [abstract]. Ann Emerg Med. 2008; 52(4 Suppl):S98.
Rose KM, Rosamond WD, Huston SL, Murphy CV, Tegeler CH. Predictors of time from hospital arrival to initial brain-imaging among suspected stroke patients: the North Carolina Collaborative Stroke Registry. Stroke. 2008; 39(12):3262-3267.
Asimos AW, Rosamond WD, Rose KM, Howard AG, Murphy CV, Tegeler CH, Coleman SW. MRI use in TIA patients: variations by Joint Commission Stroke Center certification status and implications for a revised tissue-based definition of TIA [abstract]. Stroke. 2008; 39(2):584.
Kim YJ, Tegeler CH. Indications for carotid artery surgery and stent: the role of carotid ultrasound. Curr Cardiol Rep. 2008; 10(1):17-24.
Qureshi AI, Alexandrov AV, Tegeler CH, Hobson RW II, Baker JD, Hopkins LN. Guidelines for screening of extracranial carotid artery disease: a statement for healthcare professionals from the multidisciplinary Practice Guidelines Committee of the American Society of Neuroimaging;. J Neuroimaging. 2007; 17(1):19-47.
Qureshi AI, Alexandrov AV, Tegeler CH, Hobson RW, Baker JD, Hopkins LN. Highlights of the guidelines for screening of extracranial carotid artery disease: a statement for healthcare professionals from the Multidisciplinary Practice Guidelines Committee of the American Society of Neuroimaging;. J Endovasc Ther. 2007; 14(4):469-474.
Rose KM, Rosamond WD, Huston SL, Murphy CV, Tegeler CH. Predictors of time to initial brain imaging among patients in the North Carolina Collaborative Stroke Registry [abstract]. Circulation. 2007; 115(8):e260.
Alexandrov AV, Sloan MA, Wong LKS, Douville C, Razumovsky AY, Koroshetz WJ, Kaps M, Tegeler CH. Practice standards for transcranial Doppler ultrasound: Part I–test performance. J Neuroimaging. 2007; 17(1):11-18.
Bots ML. Visseren FL, Evans GW, Riley WA, Revkin JH, Tegeler CH, Shear CL, Duggan WT, Vicari RM, Grobbee DE, et al. Torcetrapib and carotid intima-media thickness in mixed dyslipidaemia (RADIANCE 2 study): a randomised, double-blind trial. Lancet. 2007; 370(9582):153-160.
Schminke U, Motsch L, Lien L-M, Tan T-Y, Bond MG, Toole JF, Tegeler CH. Screening for high-grade carotid stenosis using a portable ultrasonography instrument. J Neuroimaging. 2006; 16(3):252-259.
Ausavarungnirun P, Sabio H, Kim J, Tegeler CH. Dynamic vascular analysis shows a hyperemic flow pattern in sickle cell disease. J Neuroimaging. 2006; 16(4):311-317.